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N-Methyl-2-pyrrolidone

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N-Methyl-2-pyrrolidone Specification

Appearance
Clear, colorless to pale yellow liquid

Solubility
Miscible with water and most organic solvents

Molecular Weight
99.13 g/mol

Ph Level
Neutral to slightly basic (pH ~7-8) in aqueous solution

Density
1.028 Gram per cubic centimeter(g/cm3)

Odour
Mild, amine-like odor

Storage Instructions
Store in cool, dry, well-ventilated place, away from heat and sources of ignition. Seal container tightly after use.

Chemical Name
N-Methyl-2-pyrrolidone

Other Names
1-Methyl-2-pyrrolidone, NMP

Classification
Organic Solvent

CAS No
872-50-4

Type
Industrial Grade

Application
Used in petrochemical processing, polymers, pharmaceuticals, electronics, and as paint stripper.

Application Method
Direct use or as a solvent in formulations.

Raw Material
Based on gamma-butyrolactone and methylamine derivatives.

Physical State
Liquid

Usage
Solvent in chemical and pharmaceutical industries, extraction, coating applications.

Shelf Life
24 months when properly stored.

Purity(%)
99.5% min

Drying Time
Depends on application, typically fast evaporating.

Best Before
2 years from manufacturing date

Melting Point
-24°C

Packaging Size
200 kg drum, 20 kg pail

Viscosity
1.67 mPa·s at 25°C

Refractive Index
1.4715 at 20°C

Boiling Point
202°C

Autoignition Temperature
245°C

Flash Point
91°C (closed cup)

Vapor Pressure
0.32 mmHg at 25°C

HS Code
29339900

Hazard Statement
Harmful if inhaled or in contact with skin, may cause serious eye irritation.

About N-Methyl-2-pyrrolidone

N-Methyl-2-pyrrolidone (NMP) is an organic compound consisting of a 5-membered lactam. It is a colorless liquid, although impure samples can appear yellow. It is miscible with water and with most common organic solvents. It also belongs to the class of dipolar aprotic solvents such as dimethylformamide and dimethyl sulfoxide. It is used in the petrochemical and plastics industries as a solvent, exploiting its nonvolatility and ability to dissolve diverse materials.

NMP is used to recover certain hydrocarbons generated in the processing of petrochemicals, such as the recovery of 1,3-butadiene and acetylene. It is used to absorb hydrogen sulfide from sour gas and hydrodesulfurization facilities. Due to its good solvency properties NMP is used to dissolve a wide range of polymers. It is also used as a solvent for surface treatment of textiles, resins, and metal coated plastics or as a paint stripper. It is utilized as a solvent in the commercial preparation of polyphenylene sulfide. In the pharmaceutical industry, N-methyl-2-pyrrolidone is used in the formulation for drugs by both oral and transdermal delivery routes.[4] It is also used heavily in lithium ion battery fabrication, as a solvent for electrode preparation, though there is much effort to replace it with solvents of less environmental concern, like water.

Versatility Across Industries

N-Methyl-2-pyrrolidones exceptional solvency and compatibility make it invaluable in multiple sectors. Whether its dissolving polymers for battery production, acting as a carrier in pharmaceuticals, or assisting in electronics fabrication, its utility spans a wide industrial landscape. Its ability to blend with both water and organic solvents further enhances its applications.

Safe Handling and Storage Protocols

Proper storage is critical when working with NMP. Always keep containers tightly sealed and store in cool, dry, well-ventilated areas away from heat sources and ignition risks. Adhering to these guidelines ensures longevity of the solventup to 24 monthsand mitigates potential hazards due to its classification as harmful by inhalation or skin contact.

FAQs of N-Methyl-2-pyrrolidone:

Q: How should N-Methyl-2-pyrrolidone be stored to maintain its quality?

A: NMP should be stored in a cool, dry, and well-ventilated location, away from heat and sources of ignition. Containers must be tightly sealed after each use to ensure stability and maintain its 24-month shelf life.

Q: What are the main industrial applications of NMP?

A: NMP is widely employed as a solvent in petrochemical processing, pharmaceuticals, polymers production, electronics manufacturing, and as a paint stripper due to its excellent solvency and compatibility with various substances.

Q: When is it best to use NMP as a solvent in formulations?

A: NMP is ideal for situations requiring dissolution of polymers, resins, or active pharmaceutical ingredients, or when effective extraction and fast evaporation are needed in coating and electronic applications.

Q: Where can NMP be sourced in India?

A: NMP is available through industrial distributors and suppliers across India, offered in standard packaging such as 20 kg pails and 200 kg drums to accommodate diverse commercial and manufacturing needs.

Q: What process is involved in applying NMP as a paint stripper or solvent?

A: NMP can be applied directly to surfaces or incorporated into formulation blends. Its fast-evaporating nature facilitates efficient removal or solubilization of coatings, adhesives, or residues during the process.

Q: How is NMP beneficial in electronics and pharmaceutical manufacturing?

A: NMPs purity (99.5% min) and miscibility with water and organic solvents make it ideal for producing high-quality coatings, dissolving challenging substances, and facilitating complex synthesis in electronics and pharmaceutical sectors.

Q: What safety precautions should be taken when handling NMP?

A: Personal protective equipment such as gloves and protective eyewear should always be worn, as NMP can cause harm if inhaled or upon skin contact, and may induce serious eye irritation. Always handle in ventilated areas.

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